My fiance and I purchased the 3 day NYPass. I planned every minute of every day! I highly recommend planning to the area of NY so there's less travel involved. The guidebook was indispensible, even worth the ridiculous postage fees to australia. We never had a problem using the cards.
We managed to use them at: The Met, The Museum of Sex, The Empire State Building/The virtual show thing, The World trade Centre memorial, The Statue of Liberty/Ellis Island ferry, Bowling at Times Square, Dialog in the Dark, Ripleys Believe it or Not, Discounted Broadway tickets and the Heartland Brewery.
We did have some other things planned, but the weather got the better of us. We wouldn't have seen half of those things, or have done nearly as many without the NYPass. My other recommendation is to wear really comfy shoes - you do a lot of walking!
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